| Dec 31, 2020 | Dec 31, 2021 | Dec 31, 2022 |
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Net loss | -12,703,197 | -12,611,197 | -5,573,957 |
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Stock based compensation | 2 | 3 | 4 |
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Warrant issuance costs | - | - | 898,023 |
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Fair Value Adjustment of Warrants | 2 | - | -8,405,000 |
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Change in fair value of derivative liability | - | - | 2 |
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Consulting services paid by issuance of common stock | 120,000 | 27,159 | 359,356 |
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Issuance Of Stock And Warrants For Services | 380,740 | 560,033 | 196,603 |
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Depreciation expense | 4,872 | 4,966 | 5,714 |
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Decrease (Increase) in prepaid expenses | 312,177 | 356,492 | -183,045 |
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(Decrease) increase in accounts payable | - | 36,172 | -636,300 |
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(Decrease) increase in accrued expenses | 286,179 | 346,250 | -161,692 |
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Total adjustments | 5 | 4 | -5,637,288 |
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Net Cash Used in Operating Activities | -8,102,398 | -8,710,725 | -11,211,245 |
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Purchase of fixed assets | 5,413 | 3,199 | 7,414 |
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Net Cash Used in Investing Activities | -5,413 | -3,199 | -7,414 |
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Private placement of preferred stock, net of transaction costs | - | - | 14 |
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Proceeds from Issuance of Private Placement | - | 24 | - |
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Proceeds from Warrant Exercises | - | 13 | 553,150 |
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Cash in lieu of shares for reverse stock split | - | 1,529 | - |
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Net Cash Provided by Financing Activities | -3,479,172 | 37 | 14 |
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NET INCREASE IN CASH AND EQUIVALENTS | -11,586,983 | 28 | 3 |
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Temporary Equity, Accretion of Dividends | - | - | 115,890 |
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Initial fair value of warrant liability pursuant to private placement of Preferred Stock and Warrants | - | - | 10 |
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Initial fair value of derivative liability pursuant to private placement of Preferred Stock and Warrants | - | - | 2 |
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