PROTHENA CORP PUBLIC LTD COPRTA
| Dec 31,
2013 | Dec 31,
2014 | Dec 31,
2015 | Dec 31,
2016 | Dec 31,
2017 | Dec 31,
2018 | Dec 31,
2019 | Dec 31,
2020 | Dec 31,
2021 | Dec 31,
2022 | Dec 31,
2023 |
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| Net income (loss) | -41 | -7 | -81 | -160 | -153 | -156 | -78 | -111 | 67 | -117 | -147 |
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| Depreciation and amortization | 1 | 1 | 1 | 2 | 3 | 3 | 2 | 2 | 1 | 1 | 1 |
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| Share-based compensation | 3 | 6 | 10 | 25 | 27 | - | - | - | - | 31 | 41 |
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| Deferred income taxes | -1 | -1 | -1 | -3 | -2 | -2 | -1 | -2 | 5 | -11 | -16 |
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| Reduction in the carrying amount of right-of-use assets | - | - | - | - | - | - | - | - | - | 6 | 7 |
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| Loss on disposal of fixed assets | - | - | - | - | - | - | - | - | - | -0 | -0 |
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| Prepaid expenses and other assets | 1 | 2 | 1 | -3 | 7 | -9 | -1 | -1 | 5 | 11 | 3 |
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| Accounts receivable | - | 2 | -1 | -0 | 0 | -0 | - | -0 | -0 | - | 5 |
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| Deferred revenue | - | - | - | - | - | 110 | - | - | 0 | -14 | -29 |
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| Prepaid expenses and other assets | 1 | 2 | 1 | -3 | 7 | -9 | -1 | -1 | 5 | 11 | 3 |
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| Accounts payable, accruals and other liabilities | 6 | 5 | 11 | 15 | 0 | -26 | -0 | 8 | -0 | 12 | 23 |
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| Deferred revenue | - | - | - | - | - | 110 | - | - | 0 | -14 | -29 |
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| Operating lease liabilities | - | - | - | - | - | - | - | - | -6 | -6 | -6 |
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| Accounts payable, accruals and other liabilities | 6 | 5 | 11 | 15 | 0 | -26 | -0 | 8 | -0 | 12 | 23 |
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| Net cash provided by (used in) operating activities | -32 | -1 | -62 | -117 | -131 | -28 | -53 | -80 | 93 | -109 | -134 |
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| Operating lease liabilities | - | - | - | - | - | - | - | - | -6 | -6 | -6 |
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| Net cash provided by (used in) operating activities | -32 | -1 | -62 | -117 | -131 | -28 | -53 | -80 | 93 | -109 | -134 |
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| Purchases of property and equipment | 1 | 1 | 1 | 17 | 4 | 2 | 1 | 0 | 1 | 0 | 3 |
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| Net cash used in investing activities | -1 | -0 | -1 | -17 | -4 | -2 | -1 | -0 | -1 | -0 | -3 |
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| Proceeds from disposal of fixed assets | 0 | 0 | - | - | 0 | 0 | 0 | - | - | - | 0 |
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| Net cash used in investing activities | -1 | -0 | -1 | -17 | -4 | -2 | -1 | -0 | -1 | -0 | -3 |
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| Public Offering | - | - | - | - | - | - | - | - | - | 173 | 21 |
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| At-The-Market Offering | - | - | - | - | - | - | - | - | 100 | - | - |
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| Proceeds from Issuance of Common Stock | 85 | 117 | 131 | 129 | 150 | - | - | - | 78 | - | - |
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| Proceeds from issuance of ordinary shares in at-the market offering, net | - | - | - | - | - | - | - | - | - | 51 | 3 |
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| Proceeds from Stock Options Exercised | - | 0 | 6 | 11 | 18 | 5 | 0 | 0 | 16 | 18 | 22 |
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| Net cash provided by financing activities | 84 | 118 | 141 | 154 | 165 | 40 | 0 | 0 | 190 | 241 | 45 |
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| Net increase (decrease) in cash, cash equivalents and restricted cash | - | - | - | - | 31 | 10 | -53 | -80 | 282 | 132 | -92 |
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| Income Taxes Paid, Net | - | - | - | - | - | - | 2 | 1 | 1 | 3 | 2 |
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| Noncash or Part Noncash Acquisition, Fixed Assets Acquired | 0 | - | 0 | 1 | 0 | 0 | 0 | - | - | - | 0 |
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| Receivable from option exercises | - | - | - | - | - | - | - | - | 0 | 0 | - |
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| Receivable from option exercises | - | - | - | - | - | - | - | - | 0 | 0 | - |
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| Noncash or Part Noncash Acquisition, Fixed Assets Acquired | 0 | - | 0 | 1 | 0 | 0 | 0 | - | - | - | 0 |
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| Right-of-use assets obtained in exchange for lease obligations | - | - | - | - | - | - | 29 | - | - | 0 | 4 |
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| Reclassification of prepaid lease payments to right-of-use assets upon lease commencement | - | - | - | - | - | - | - | - | - | - | 8 |
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| Public Offering | - | - | - | - | - | - | - | - | - | 0 | - |
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| At-The-Market Offering | - | - | - | - | - | - | - | - | - | 0 | 0 |
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