| Dec 31, 2016 | Dec 31, 2017 | Dec 31, 2018 | Dec 31, 2019 | Dec 31, 2020 | Dec 31, 2021 | Dec 31, 2022 | Dec 31, 2023 | Dec 31, 2024 |
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| Net loss | -13 | -31 | -31 | -46 | -60 | -66 | -78 | -52 | -16 |
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| Issuance of Common Shares Equity Fee on Equity Offering | - | - | - | - | - | - | - | - | 0 |
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| Common Shares Issuable Annual Stock Dividend | - | - | - | - | - | - | - | - | 1 |
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| Research and development - licenses acquired | - | - | - | 1 | 2 | 2 | 0 | 0 | 0 |
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| Stock-based compensation expenses | - | 2 | 5 | 3 | 3 | 3 | 2 | 1 | -0 |
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| Depreciation | - | 0 | 1 | 1 | 2 | 2 | 3 | 2 | 1 |
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| Amortization of debt discount | 1 | - | - | 1 | 2 | - | 0 | 0 | - |
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| Amortization of operating lease right-of-use assets | - | - | - | - | - | 0 | 0 | 0 | 0 |
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| Loss on disposal of property and equipment | - | - | - | - | - | - | - | - | -0 |
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| Asset impairment | - | - | - | - | - | - | - | - | 4 |
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| Gain on sale of property and equipment | - | - | - | - | - | - | - | 1 | - |
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| Loss on extinguishment of debt | - | - | - | - | - | - | - | -3 | - |
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| Gain on lease modification | - | - | - | - | - | - | - | -0 | 0 |
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| Prepaid expenses and other assets | - | - | - | 1 | 0 | 0 | 1 | -1 | -1 |
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| Related Party | - | - | - | - | - | - | - | -0 | - |
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| Non related party | - | - | - | - | - | - | - | 4 | -0 |
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| Other receivables | - | - | - | 0 | -0 | 0 | -0 | - | - |
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| Accounts payable and accrued expenses | - | - | - | 0 | 3 | -0 | 5 | 0 | -3 |
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| Payable and accrued expenses - related party | -0 | 0 | 0 | 0 | -0 | 0 | 0 | 0 | 2 |
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| Deferred income | - | - | - | - | - | 0 | - | - | -0 |
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| Lease liabilities | - | - | - | -0 | -0 | 0 | 0 | 1 | 0 |
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| Net cash used in operating activities | - | -13 | -19 | -34 | -37 | -54 | -65 | -49 | -11 |
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| Purchase of research and development licenses | - | 2 | 1 | 1 | 2 | 1 | 0 | 0 | - |
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| Proceeds from the sale of property and equipment | - | - | - | - | - | - | 0 | 6 | - |
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| Purchase of fixed assets | - | - | 7 | 2 | 2 | 4 | 3 | 0 | - |
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| Net cash from investing activities | - | -29 | 1 | 14 | -4 | -5 | -3 | 6 | - |
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| Payment of debt | - | - | - | - | - | - | - | 30 | - |
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| Proceeds from Issuance of Common Stock | - | - | - | 32 | 37 | - | - | - | 7 |
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| Offering costs for the issuance of common shares - Equity Offerings | - | - | - | 2 | 2 | - | - | - | 1 |
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| Proceeds from issuance of common shares - At-the-Market Offering | - | - | - | 23 | 60 | 72 | 7 | 0 | 3 |
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| Offering costs for the issuance of common shares - At-the-Market Offering | - | - | - | 1 | 1 | 1 | 0 | 0 | 0 |
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| Proceeds from Warrant Exercises | - | - | 0 | - | - | - | - | - | 4 |
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| Proceeds from Stock Plans | - | - | - | - | 0 | 0 | 0 | 0 | 0 |
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| Net cash provided by (used in) financing activities | - | 50 | 0 | 65 | 78 | 71 | 34 | -26 | 11 |
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| Net change in cash, cash equivalents and restricted cash | - | - | - | 45 | 36 | 12 | -34 | -70 | -0 |
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| Cash paid for interest | - | 0 | - | 1 | 2 | - | 3 | 1 | - |
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| Stock Issued | 0 | 4 | 10 | 2 | 5 | 8 | 4 | 1 | 1 |
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