| Dec 31, 2017 | Dec 31, 2018 | Dec 31, 2019 | Dec 31, 2020 | Dec 31, 2021 | Dec 31, 2022 | Dec 31, 2023 | Dec 31, 2024 |
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| Profit before tax | 2,227 | 1,993 | 1,548 | 3,916 | -265 | 2,501 | 6,899 | 8,691 |
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| Finance income and expense | - | - | - | - | - | - | -1,282 | -1,284 |
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| Share of after tax losses of associates and joint ventures | - | - | - | - | - | - | -12 | -28 |
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| Depreciation, amortisation and impairment | - | - | - | - | - | - | 5,387 | 6,688 |
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| Increase in trade and other receivables | 83 | -523 | -898 | -739 | -961 | -1,349 | -1,425 | -1,624 |
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| (Increase)/decrease in inventories | -548 | -13 | -316 | -621 | 1,577 | 3,941 | -669 | -131 |
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| Increase in trade and other payables and provisions | -415 | 103 | -868 | -1,721 | -1,405 | -1,165 | -2,394 | -862 |
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| Gains on disposal of intangible assets | -1,518 | -1,885 | -1,243 | -1,030 | -513 | -104 | -251 | -64 |
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| Contingent consideration, fair value movement | 109 | -495 | -614 | -272 | 14 | 82 | 549 | 311 |
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| Non-cash and other movements | -524 | -290 | 378 | -276 | 95 | -692 | -386 | -121 |
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| Cash generated from operations | 4,730 | 3,831 | 4,861 | 7,094 | 8,427 | 12,280 | 13,792 | 15,924 |
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| Interest paid | 698 | 676 | 774 | 733 | 721 | 849 | 1,081 | 1,313 |
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| Tax paid | 454 | 537 | 1,118 | 1,562 | 1,743 | 1,623 | 2,366 | 2,750 |
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| Net cash inflow from operating activities | 3,578 | 2,618 | 2,969 | 4,799 | 5,963 | 9,808 | 10,345 | 11,861 |
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| Acquisition of subsidiaries, net of cash acquired | - | - | - | - | 9,263 | 48 | 189 | 2,771 |
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| Payments upon vesting of employee share awards attributable to business combinations | - | - | - | - | 211 | 215 | 84 | 3 |
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| Payment of contingent consideration from business combinations | 434 | 349 | 709 | 822 | 643 | 772 | 826 | 1,008 |
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| Purchase of property, plant and equipment | 1,326 | 1,043 | 979 | 961 | 1,091 | 1,091 | 1,361 | 1,924 |
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| Disposal of property, plant and equipment | 83 | 12 | 37 | 106 | 13 | 282 | 132 | 55 |
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| Purchase of intangible assets | 294 | 328 | 1,481 | 1,645 | 1,109 | 1,480 | 2,417 | 2,662 |
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| Disposal of intangible assets | 1,376 | 2,338 | 2,076 | 951 | 587 | - | 291 | 123 |
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| Movement in profit-participation liability | - | - | 150 | 40 | 20 | - | 190 | - |
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| Purchase of non-current asset investments | 96 | 102 | 13 | 119 | 184 | 45 | 136 | 96 |
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| Disposal of non-current asset investments | 70 | 24 | 18 | 1,381 | 9 | 42 | 32 | 78 |
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| Other inflows (outflows) of cash, classified as investing activities | -345 | 405 | 194 | 745 | 96 | -114 | 97 | 30 |
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| Payments to associates and joint ventures | 76 | 187 | 74 | 8 | 92 | 26 | 80 | 158 |
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| Disposal of investments in associates and joint ventures | - | - | - | - | 776 | - | - | 13 |
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| Interest received | 164 | 193 | 124 | 47 | 34 | 60 | 287 | 343 |
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| Net cash outflow from investing activities | -2,328 | 963 | -657 | -285 | -11,058 | -2,960 | -4,064 | -7,980 |
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| Net cash inflow before financing activities | 1,250 | 3,581 | 2,312 | 4,514 | -5,095 | 6,848 | 6,281 | 3,881 |
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| Proceeds from issuing shares | 43 | 34 | 3,525 | 30 | 29 | 29 | 33 | 38 |
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| Own shares purchased by Employee Benefit Trusts | - | - | - | - | 149 | - | - | 81 |
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| Issue of loans and borrowings | 1,988 | 2,971 | 500 | 2,968 | 12,929 | - | 3,816 | 6,492 |
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| Repayment of loans and borrowings | 1,750 | 1,400 | 1,500 | 1,609 | 4,759 | 1,271 | 4,942 | 4,652 |
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| Dividends paid | 3,519 | 3,484 | 3,592 | 3,572 | 3,856 | 4,364 | 4,481 | 4,629 |
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| Hedge contracts relating to dividend payments | 20 | 67 | -4 | 101 | 29 | 127 | 19 | -16 |
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| Repayment of obligations under leases | - | - | 186 | 207 | 240 | 244 | 268 | 316 |
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| Movement in short-term borrowings | - | - | - | - | - | - | - | -31 |
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| Payment of Acerta Pharma share purchase liability | - | - | - | - | - | 920 | 867 | 833 |
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| Net cash outflow from financing activities | -2,936 | -2,044 | -1,765 | -2,203 | 3,649 | -6,823 | -6,567 | -3,996 |
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| Net (decrease)/increase in Cash and cash equivalents in the period | -1,686 | 1,537 | 547 | 2,311 | -1,446 | 25 | -286 | -115 |
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| Exchange rate effects | -66 | -38 | 5 | 12 | -62 | -80 | -60 | -93 |
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