| Dec 31,
2020 | Dec 31,
2021 | Dec 31,
2022 | Dec 31,
2023 | Dec 31,
2024 |
|---|
| Net (loss) earnings | -670 | -1,269 | 2,079 | 55 | -634 |
|---|
| Depreciation and amortization | 2,216 | 4,507 | 3,028 | 2,741 | 2,893 |
|---|
| Deferred income tax benefit | -213 | 676 | -26 | -387 | -768 |
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| Litigation settlements and other contingencies, net | -101 | -324 | 2 | -87 | -274 |
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| Loss (gain) on disposal of business | - | - | 1,754 | -240 | -399 |
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| Share-based compensation expense | 79 | 111 | 116 | 181 | 146 |
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| Acquired IPR&D | - | - | - | - | -12 |
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| Other non-cash items | -366 | -412 | -434 | -595 | -298 |
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| Accounts receivable | -79 | -59 | 240 | -79 | -300 |
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| Inventories | 742 | 428 | 260 | 613 | 723 |
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| Trade accounts payable | -83 | -70 | 170 | 315 | 36 |
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| Income taxes | 4 | -700 | 25 | -77 | 219 |
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| Other operating assets and liabilities, net | -46 | 667 | 618 | 415 | 151 |
|---|
| Net cash provided by operating activities | 1,232 | 3,017 | 2,953 | 2,800 | 2,303 |
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| Cash paid for acquisitions, net of cash acquired | -416 | -277 | - | 668 | 350 |
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| Capital expenditures | 243 | 457 | 406 | 377 | 326 |
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| Payments for product rights and other, net | 438 | 52 | 37 | 98 | 21 |
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| Proceeds from sale of property, plant and equipment | 2 | 18 | 14 | 14 | 3 |
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| Purchases of IPR&D | - | - | - | - | -12 |
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| Proceeds from Divestiture of Businesses | 20 | 97 | 1,950 | 364 | 2,507 |
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| Purchase of marketable securities | 105 | 30 | 30 | 26 | 26 |
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| Proceeds from the sale of marketable securities | 47 | 30 | 30 | 26 | 26 |
|---|
| Net cash provided by (used in) investing activities | -301 | -118 | 1,521 | -764 | 1,801 |
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| Proceeds from issuance of long-term debt | 983 | 1,710 | 1,876 | 0 | - |
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| Payments of long-term debt | 2,484 | 4,201 | 3,663 | 1,250 | 3,714 |
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| Payments of financing fees | 2 | 7 | 2 | 1 | 5 |
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| Change in short-term borrowings, net | 1,100 | 392 | -1,493 | 0 | - |
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| Purchase of ordinary shares | - | - | - | 250 | 250 |
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| Taxes paid related to net share settlement of equity awards | 8 | 17 | 17 | 38 | 53 |
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| Contingent consideration payments | 49 | 29 | 19 | 8 | 32 |
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| Cash dividends paid | - | 399 | 582 | 576 | 575 |
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| Non-contingent payments for product rights | 143 | 456 | - | 10 | - |
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| Issuance of common stock | - | - | 3 | 3 | 3 |
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| Other items, net | -3 | -5 | 19 | -173 | 295 |
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| Net cash used in financing activities | -606 | -3,012 | -3,878 | -2,302 | -4,330 |
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| Effect on cash of changes in exchange rates | - | - | -39 | -2 | -31 |
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| Net (decrease) increase in cash, cash equivalents and restricted cash | 359 | -144 | 556 | -269 | -257 |
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| Income taxes | 324 | 642 | 735 | 571 | 514 |
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| Interest | 555 | 685 | 643 | 612 | 561 |
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