| Dec 31, 2021 | Dec 31, 2022 | Dec 31, 2023 | Dec 31, 2024 |
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| Net income | 1,351 | 917 | 1,023 | 864 |
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| Depreciation | 92 | 96 | 120 | 132 |
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| Amortization | 103 | 116 | 116 | 145 |
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| Impairment of assets | 7 | 9 | - | - |
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| Acquired in-process research and development and milestones | - | - | 8 | 81 |
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| Contingent consideration | - | - | - | 11 |
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| Deferred income tax benefit | -288 | -18 | -485 | -160 |
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| Stock-based compensation | 59 | 75 | 101 | 105 |
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| Unrealized foreign exchange (gain) loss | - | 18 | -40 | 2 |
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| Other | -12 | -26 | -31 | -41 |
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| Accounts receivable | 277 | 123 | 212 | -383 |
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| Inventories | 138 | 220 | 230 | 131 |
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| Other current assets | -353 | 43 | 10 | 236 |
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| Trade accounts payable | 663 | -237 | 163 | -157 |
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| Accrued and other current liabilities | 329 | 172 | 102 | -101 |
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| Income taxes payable | -119 | 7 | 16 | -65 |
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| Other | -55 | 8 | -16 | -29 |
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| Net Cash Flows Provided by Operating Activities | - | - | - | 939 |
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| Capital expenditures | 192 | 196 | 251 | 175 |
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| Proceeds from sale of property, plant and equipment | 7 | 7 | 1 | 4 |
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| Acquired in-process research and development and milestones | 104 | 107 | 8 | 71 |
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| Dermavant acquisition, net of cash acquired | - | - | - | 166 |
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| Purchase of product rights and asset acquisition | 192 | 124 | 2 | 105 |
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| Net Cash Flows Used in Investing Activities | - | - | - | -513 |
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| Proceeds from debt | 9,470 | - | 80 | 1,186 |
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| Repayments of debt | 112 | 108 | 338 | 1,197 |
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| Payment of long-term debt issuance costs | 118 | - | - | 38 |
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| Net transfers to Merck & Co., Inc. | -440 | 24 | - | - |
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| Employee withholding taxes related to stock-based awards | - | 11 | 17 | 22 |
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| Dividend payments | 145 | 290 | 294 | 297 |
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| Net Cash Flows Used in Financing Activities | - | - | - | -368 |
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| Effect of Exchange Rate Changes on Cash and Cash Equivalents | 23 | -36 | 17 | -76 |
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| Net Decrease in Cash and Cash Equivalents | 667 | -31 | -13 | -18 |
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