Ampio Pharmaceuticals, Inc.【AMPE】
| Dec 31, 2011 | Dec 31, 2012 | Dec 31, 2013 | Dec 31, 2014 | Dec 31, 2015 | Dec 31, 2016 | Dec 31, 2017 | Dec 31, 2018 | Dec 31, 2019 | Dec 31, 2020 | Dec 31, 2021 | Dec 31, 2022 | Dec 31, 2023 |
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| Net loss | - | - | -24,008,558 | -39,048,772 | -33,713,917 | -19,163,629 | -51,891,945 | 34 | -13,630,000 | -15,894,000 | -17,075,000 | -16,337,000 | -8,632,000 |
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| Share-based Compensation | 3 | 5 | 8 | 8 | 6 | 2 | 744,870 | 443,786 | 405,000 | 1 | 3 | 1 | 159,000 |
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| Restricted stock award compensation, forfeitures | - | - | - | - | - | - | - | - | - | - | - | 509,000 | - |
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| Depreciation and amortization | 42,551 | 104,947 | 242,627 | 439,098 | - | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 122,000 |
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| Long-lived assets impairment | - | - | - | - | - | - | - | - | - | - | - | 2 | - |
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| Right-of-use asset impairment | - | - | - | - | - | - | - | - | - | - | - | 0 | - |
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| Loss on sale of fixed assets | - | - | - | - | - | - | - | -123,176 | - | -73,000 | - | - | -56,000 |
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| Net gain from elimination of ARO obligation | - | - | - | - | - | - | - | - | - | - | - | - | 289,000 |
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| Accretion of asset retirement obligation | - | - | - | - | - | - | - | - | - | - | - | - | 5,000 |
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| Derivative gain | -1,555,497 | 205,768 | -516,840 | - | -78,038 | -915,141 | -36,218,832 | 45 | 5 | -0 | 4 | 6 | - |
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| Increase in insurance recovery receivable | - | - | - | - | - | - | - | - | - | - | - | - | 920,000 |
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| (Increase) decrease in prepaid expenses and other | - | - | - | - | 1 | -80,684 | -18,473 | 179,465 | 1 | -571,000 | 593,000 | -1,064,000 | 51,000 |
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| Increase (decrease) in accounts payable and accrued expenses | - | - | - | - | - | -1,095,074 | 2 | -1,460,877 | 3 | -2,475,000 | 3 | -3,959,000 | 1 |
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| Decrease in lease liability | - | - | - | - | - | - | - | - | -70,000 | -81,000 | -89,000 | -79,000 | -265,000 |
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| Net cash used in operating activities | -9,131,662 | -9,715,163 | -19,133,157 | - | - | -14,624,972 | -11,407,947 | -12,138,023 | -15,383,000 | -15 | -14,089,000 | -21,128,000 | -8,564,000 |
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| Net cash used in investing activities | -119,705 | 15,000 | -1,665,239 | - | - | -6,844 | -72,325 | -564,276 | -22,000 | -63,000 | -97,000 | - | - |
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| Proceeds from Sale of Common Stock in Connection with At The Market Equity Offering Program | - | - | - | - | - | - | - | - | - | 26 | 11 | - | 98,000 |
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| Costs related to sale of common stock in connection with the "at-the-market" equity offering program | - | - | - | - | - | - | - | - | - | 1 | 512,000 | - | 98,000 |
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| Costs related to the sale of common stock and warrants in connection with the registered direct offering | - | - | - | - | - | - | - | - | - | - | 2 | 32,000 | - |
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| Funding of tax obligation relative to shares withheld in connection with restricted stock awards | - | - | - | - | - | - | - | - | - | - | 186,000 | 79,000 | - |
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| Net cash used in financing activities | 25 | 41 | 70 | - | - | 4 | 15 | 12 | 14 | 26 | 31 | -111,000 | - |
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| Net change in cash and cash equivalents | - | - | - | - | - | - | - | - | -1,053,000 | 11 | 17 | -21,239,000 | -8,564,000 |
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| Commercial insurance premium financing agreement | - | - | - | - | - | - | - | - | - | 1 | 1 | 1 | 703,000 |
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| Recognition of asset retirement obligation | - | - | - | - | - | - | - | - | - | - | - | 282,000 | - |
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